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JAK2 Inhibitor V
CAS No. 195371-52-9
JAK2 Inhibitor V ( NSC 42834; Janus-Associated Kinase Inhibitor V )
Catalog No. M18188 CAS No. 195371-52-9
NSC 42834(JAK2 Inhibitor V, Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 30 | In Stock |
|
| 5MG | 47 | In Stock |
|
| 10MG | 69 | In Stock |
|
| 25MG | 143 | In Stock |
|
| 50MG | 259 | In Stock |
|
| 100MG | 478 | In Stock |
|
| 500MG | 1062 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameJAK2 Inhibitor V
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NoteResearch use only, not for human use.
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Brief DescriptionNSC 42834(JAK2 Inhibitor V, Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.
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DescriptionNSC 42834, also known as JAK2 Inhibitor V, is an inhibitor of the autophosphorylation of wild type and V617F mutant forms of JAK2, displaying IC50 values between 10 and 30 μM.
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SynonymsNSC 42834; Janus-Associated Kinase Inhibitor V
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PathwayOthers
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TargetOther Targets
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RecptorJAK2; JAK2 (V617F)
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number195371-52-9
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Formula Weight344.45
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Molecular FormulaC23H24N2O
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Purity98%
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SolubilityDMSO : ≥ 43 mg/mL; 124.84 mM
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SMILESO=C(C(CCc1ccccn1)(CCc1ccccn1)C)c1ccccc1
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Chemical Name2-methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jacqueline Sayyah, et al. Mol Y Ther 2008;7(8):2308-18.
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